Fast and Simple LC-MS/MS Method for Rifampicin Quantification in Human Plasma

<table class="fixed-width table-group" id="tab3"><tr><td><table class="table"><colgroup><col style="width:5.53em"/><col style="width:7.78em"/><col style="width:5.75em"/><col style="width:6.44em"/></colgroup><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left"> </td><td class="align_center" colspan="3">Stability (%)</td></tr><tr class="thead"><td class="align_left">QC (<i>μ</i>g/L)</td><td class="align_center">Freeze and thaw</td><td class="align_center">Short-term</td><td class="align_center">Autosampler</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">15</td><td class="align_center">3.03</td><td class="align_center">5.06</td><td class="align_center">-9.88</td></tr><tr><td class="align_left">750</td><td class="align_center">-10.23</td><td class="align_center">-1.89</td><td class="align_center">N.D.</td></tr><tr><td class="align_left">10000</td><td class="align_center">3.00</td><td class="align_center">-3.80</td><td class="align_center">N.D.</td></tr><tr><td class="align_left">30000</td><td class="align_center">1.61</td><td class="align_center">2.24</td><td class="align_center">-2.18</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>N.D. = not determined<br/></div></td></tr></table>

International Journal of Analytical Chemistry

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Table 3

Table 3: Fast and Simple LC-MS/MS Method for Rifampicin Quantification in Human Plasma 