The Determination of Parkinson’s Drugs in Human Urine by Applying Chemometric Methods

Table 4

Determination of levodopa and carbidopa in human urine using PLS and PCR methods.

	Levodopa (PLS)			Carbidopa (PLS)
Mix	Added	Found	Recovery	Added	Found	Recovery
No	(mg L^−1)	(mg L^−1)	(% mean)	(mg L^−1)	(mg L^−1)	(% mean)
1	4	3.98	99.50	4	3.97	99.25
2	8	7.98	99.75	8	7.96	99.50
3	12	11.96	99.67	12	11.97	99.75
4	16	15.98	99.88	16	15.99	99.94
5	20	19.89	99.45	20	19.98	99.90
Mean ± SD			99.65			99.67
Standard Deviation			0.177			0.29
	Levodopa (PCR)			Carbidopa (PCR)
Mix	Added	Found	Recovery	Added	Found	Recovery
No	(mg L^−1)	(mg L^−1)	(% mean)	(mg L^−1)	(mg L^−1)	(% mean)
1	4	3.96	99.00	4	3.98	99.5
2	8	7.96	99.50	8	7.98	99.75
3	12	11.97	99.75	12	11.99	99.92
4	16	15.96	99.75	16	15.98	99.88
5	20	19.98	99.90	20	19.97	99.85
Mean			99.58			99.78
Standard Deviation			0.35			0.17
	Levodopa (Classical UV-Vis)			Carbidopa (Classical UV-Vis)
Mix	Added	Found	Recovery	Added	Found	Recovery
No	(mg L^−1)	(mg L^−1)	(% mean)	(mg L^−1)	(mg L^−1)	(% mean)
1	4	3.97	99.25	4	3.95	98.75
2	8	7.95	99.38	8	7.99	99.88
3	12	11.95	99.58	12	11.96	99.67
4	16	15.93	99.56	16	15.98	99.88
5	20	19.99	99.95	20	19.96	99.80
Mean			99.54			99.60
Standard Deviation			0.26			0.48