Optimization of Flavonoid Extraction in Dendrobium officinale Leaves and Their Inhibitory Effects on Tyrosinase Activity

Table 3

Central composite design and results.

Run	Factor 1	Factor 2	Response
	Number	Ethanol; (%)	Flavonoid; (mg/50mL)
1	5	76%	30.22
2	5	79%	31.68
3	7	76%	26.27
4	7	79%	29.18
5	6	75%	26.40
6	6	80%	29.90
7	5	78%	31.40
8	7	78%	28.40
9	6	78%	36.45
10	6	78%	36.95
11	6	78%	34.13
12	6	78%	33.81
13	6	78%	34.95