Preparative Separation of Three Monoterpenes from Perilla frutescens var. crispa Using Centrifugal Partition Chromatography

Table 1

The partition coefficient (K) and separation factor (α) of compounds 1–3 in different solvent systems.

Solvent system; (-Hexane-EtOAc-EtOH-Water)	K values						α value
	Descending mode			Ascending mode
	1	2	3	1	2	3	α12	α23	α13
5:5:5:5	0.59	4.78	6.99	1.69	0.21	0.14	8.10	1.46	11.8
6:4:5:5	0.34	4.47	7.10	2.94	0.22	0.14	13.1	1.57	20.9
7:3:5:5	0.20	4.04	6.99	5.00	0.25	0.14	20.2	1.73	35.0
6:4:6:4	0.21	2.11	3.27	4.76	0.47	0.31	10.0	1.55	15.6
7:3:6:4	0.13	1.93	3.20	7.69	0.52	0.31	14.8	1.66	24.6
7:3:7:3	0.10	1.03	1.63	10.0	0.97	0.61	10.3	1.58	16.3
7:3:8:2	0.11	0.67	0.96	9.09	1.49	1.04	6.09	1.43	8.73
8:2:7:3	0.26	4.34	7.38	3.85	0.23	0.14	16.7	1.70	28.4
8:2:8:2	0.07	0.63	0.96	14.3	1.59	1.04	9.00	1.52	13.7
9:1:9:1	0.12	0.45	0.60	8.33	2.22	1.67	3.75	1.33	5.00