Determination of Atenolol and Trimetazidine in Pharmaceutical Tablets and Human Urine Using a High Performance Liquid Chromatography-Photo Diode Array Detection Method

Table 1

Analytical performance data for HPLC determination of atenolol and trimetazidine in pure form and urine samples.

Parameter	Atenolol		Trimetazidine
	Pure form	Urine	Pure form	Urine
Linearity range (μg/ml)	1.0–100	0.5-25	1.0– 100	0.25-25
Correlation coefficient (r^2)	0.9998	0.9999	0.9999	0.9995
Regression equation	Y=39.15X-5.7394	Y=0.037X-8.0947	Y=118.06X-58.05	Y=0.3464X+31.83
LOD (μg/ml)	0.30	0.11	0.18	0.05
LOQ (μg/ml)	0.99	0.38	0.60	0.16