Determination of Atenolol and Trimetazidine in Pharmaceutical Tablets and Human Urine Using a High Performance Liquid Chromatography-Photo Diode Array Detection Method

Table 3

Statistical analysis of the proposed method in standard solution and the official/reported methods [1, 38].

	Atenolol		Trimetazidine
	Proposed Method	Reported method [38]	Proposed Method	Official method [1]
Mean	100.34	99.66	100.35	98.39
SD	1.17	0.87	1.06	0.77
RSD%	1.16	0.88	1.06	1.12
Variance	1.36	0.76	1.13	0.59
N	8	5	8	3
F – test	1.8 (4.12)	-	1.09 (4.74)	-
Student’s t-test	1.11 (2.201)	-	1.93 (2.262)	-

Figures between parenthesis represent the corresponding tabulated values of t and F at P= 0.05.
Spectrophotometric method based on measurement of atenolol absorbance in 0.1 N HCl at 224.6 nm.