International Journal of Analytical Chemistry / 2020 / Article / Tab 2

Research Article

Development and Validation of UPLC-MS/MS Method for Determination of Enasidenib in Rat Plasma and Its Pharmacokinetic Application

Table 2

Recovery and matrix effect of enasidenib in rat plasma (n = 6).

AnalyteConcentration added (ng/mL)Recovery (%)Matrix effect (%)
Mean ± SDRSD (%)Mean ± SDRSD (%)

Enasidenib2.580.07 ± 2.4411.499.09 ± 13.8814.01
40082.74 ± 2.363.199.35 ± 5.755.79
80084.83 ± 1.441.8100.04 ± 1.981.98

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