Determination of Crizotinib in Mouse Tissues by LC-MS/MS and Its Application to a Tissue Distribution Study

Figure 6

Concentrations of crizotinib in the heart, muscle, and brain at 0.5 h, 2 h, 4 h, 8 h, 15 h, and 24 h after an intragastric administration of crizotinib (500 mg/kg) in healthy mice. Data are means ± SD.