A Validated Liquid Chromatographic Method for Berberine Analysis in Tissue and Application

Table 5

Results of BB at a dose of 200 mg/kg in tissues of rat (mean ± SD, n = 6, µg/g).

Tissue	1 h		2 h		4 h
	With GA	Without GA	With GA	Without GA	With GA	Without GA
Liver	0.450 ± 0.217	0.772 ± 0.343	1.814 ± 2.003	3.734 ± 1.875	0.850 ± 0.268	0.882 ± 0.132
Spleen	0.068 ± 0.037	0.0504 ± 0.023	0.114 ± 0.171	0.324 ± 0.292	0.065 ± 0.060	0.075 ± 0.065
Kidney	0.137 ± 0.148	0.397 ± 0.315	0.193 ± 0.089	0.287 ± 0.122	0.188 ± 0.052	0.241 ± 0.259

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