Research Article

A Fast and Validated HPLC Method for the Simultaneous Analysis of Five 5-HT3 Receptor Antagonists via the Quantitative Analysis of Multicomponents by a Single Marker

Figure 2

Typical HPLC chromatogram for simultaneous separation of ODT, GNT, TPT, AZT, and RMT. Chromatographic conditions were acetonitrile-0.05 mol·L−1 potassium dihydrogen phosphate (25 : 75, v/v) except the buffer pH was varied: (a) pH 3.0; (b) pH 3.5; (c) pH 4.0; (d) pH 4.5; and (e) pH 5.0.