A Fast and Validated HPLC Method for the Simultaneous Analysis of Five 5-HT₃ Receptor Antagonists via the Quantitative Analysis of Multicomponents by a Single Marker

Table 1

Regression equation, correlation coefficient (r), linear range, and detection limit of the five 5-HT3 receptor antagonists.

Compound	Regression equation	r	Linear range (μg·mL^−1)	Detection limit (μg·mL^−1)	Quantification limit (μg·mL^−1)
Azasetron	Y = 0.6321X + 1.3833	0.9996	5.0–100	0.2	0.6
Granisetron	Y = 0.6957X + 0.5444	0.9999	5.0–100	0.1	0.4
Tropisetron	Y = 1.0634X + 4.8592	0.9997	5.0–100	0.05	0.2
Ondansetron	Y = 1.8585X + 5.2914	0.9999	5.0–100	0.1	0.3
Ramosetron	Y = 2.3167X + 8.6551	0.9999	0.5–50	0.1	0.2