A Fast and Validated HPLC Method for the Simultaneous Analysis of Five 5-HT₃ Receptor Antagonists via the Quantitative Analysis of Multicomponents by a Single Marker

Table 2

Accuracy and precision results for the HPLC method.

Drug	Measured concentrations (μg/mL)	Accuracy (%)	Precision RSD (%)
			Intraday	Interday
Azasetron	10.0	99.7	1.5	1.7
	20.0	99.1	1.4	1.5
	50.0	99.2	1.2	1.8
Granisetron	10.0	101.7	0.7	1.1
	20.0	98.9	1.0	1.4
	50.0	99.0	0.8	1.4
Tropisetron	10.0	101.8	0.4	1.6
	20.0	99.3	1.6	1.8
	50.0	100.9	1.4	1.9
Ondansetron	10.0	101.8	1.1	1.5
	20.0	99.2	0.7	1.9
	50.0	98.3	0.9	1.7
Ramosetron	1.0	101.5	1.4	1.6
	3.0	101.6	1.3	1.6
	6.0	99.5	1.2	1.9