A RP-HPLC Method for the Analysis of Neostigmine Methylsulfate and Process-Related Impurities, Forced Degradation Studies, in the Injection Formulation

<table class="table-group" id="tab6"><tr><td><table class="table"><tr><td class="thead-hr" colspan="9"><hr/></td></tr><tr class="thead"><td class="align_left">Component names</td><td class="align_center">RT (min)</td><td class="align_center">RRT</td><td class="align_center">Area</td><td class="align_center">Theoretical plates</td><td class="align_center">Tailing factor</td><td class="align_center">Resolution</td><td class="align_center">Purity angle</td><td class="align_center">Purity threshold</td></tr><tr><td class="thead-hr" colspan="9"><hr/></td></tr><tr><td class="align_left">Impurity A</td><td class="align_center">4.891</td><td class="align_center">0.4739</td><td class="align_center">13357</td><td class="align_center">20867</td><td class="align_center">1.24</td><td class="align_center">6.25</td><td class="align_center">1.723</td><td class="align_center">2.678</td></tr><tr class="table-tr"><td colspan="9"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>System suitability parameters for impurity A in NMS injection.</div>

International Journal of Analytical Chemistry

tab6

Table 6

Table 6: A RP-HPLC Method for the Analysis of Neostigmine Methylsulfate and Process-Related Impurities, Forced Degradation Studies, in the Injection Formulation 

Table 6 | A RP-HPLC Method for the Analysis of Neostigmine Methylsulfate and Process-Related Impurities, Forced Degradation Studies, in the Injection Formulation 