Research Article
Study of Zuojin Pill in Treating Chronic Atrophic Gastritis by UPLC-Q-TOF/MS Based on Serum and Urine Metabolomics Combined with Network Pharmacology
Table 3
Results of integrating enrichment analysis of biomarkers with MetaboAnalyst.
| | | Number | Pathway name | Match status | value | −log () | Impact |
| | Serum | 1 | Taurine and hypotaurine metabolism | 1/8 | 0.05192 | 2.9581 | 0.42857 | | 2 | Glyoxylate and dicarboxylate metabolism | 1/32 | 0.19345 | 1.6427 | 0.21958 | | 3 | Glycine, serine, and threonine metabolism | 4/34 | 4.1098 × 10−5 | 10.1 | 0.06662 | | 4 | Glycerophospholipid metabolism | 2/36 | 0.022085 | 3.8128 | 0.04318 | | 5 | Citrate cycle (TCA cycle) | 1/20 | 0.12526 | 2.0774 | 0.03273 |
| | Urine | 6 | Citrate cycle (TCA cycle) | 2/20 | 0.0085481 | 4.762 | 0.14041 | | 7 | Glycerophospholipid metabolism | 1/36 | 0.23395 | 1.4527 | 0.09446 | | 8 | Glyoxylate and dicarboxylate metabolism | 2/32 | 0.021272 | 3.8503 | 0.05556 | | 9 | Alanine, aspartate, and glutamate metabolism | 2/28 | 0.016472 | 4.1061 | 0.04808 | | 10 | Butanoate metabolism | 1/15 | 0.1044 | 0.1044 | 0.03175 | | 11 | Purine metabolism | 1/66 | 0.38959 | 0.94266 | 0.94266 |
|
|
