HPLC-MS/MS-Mediated Analysis of the Pharmacokinetics, Bioavailability, and Tissue Distribution of Schisandrol B in Rats

Table 1

Summary of LLOQ, linear ranges, regression equations, and correlation coefficients of analytes in rat plasma and tissue homogenate samples.

Sample	Calibration curve	R^2	Linear range (ng/mL)
Plasma	y = 0.0081x − 0.0137	0.990	5–2000
Heart	y = 0.00825x − 0.00473	0.997	1–1000
Liver	y = 0.00868x − 0.00608	0.990	1–1000
Spleen	y = 0.0292x + 0.00648	0.995	1–1000
Lung	y = 0.00127x + 0.000556	0.993	1–1000
Kidney	y = 0.00443x + 0.00519	0.990	1–1000
Brain	y = 0.00445x + 0.00258	0.997	1–1000