A Rapid Screening Method for Sibutramine Hydrochloride in Natural Herbal Medicines and Dietary Supplements

Table 1

The results of partition coefficients.

System	Sample	Peak area	C^A or C^B (μg/ml)	Partition coefficients K	K (avg.)	R.S.D. % (n = 3)
1	B	13958213	340.89	36.62	36.72	1.31
	A	383660	9.31
	B	13936925	340.37	36.29
	A	386525	9.38
	B	14138345	345.29	37.24
	A	382022	9.27
2	B	13961488	340.97	42.00	40.37	3.51
	A	334942	8.12
	B	14056876	343.30	39.64
	A	357049	8.66
	B	14024944	342.52	39.47
	A	357868	8.68
3	B	14275491	348.64	45.18	46.70	3.18
	A	318567	7.72
	B	14247243	347.95	48.14
	A	298507	7.23
	B	14171506	346.10	46.77
	A	305466	7.40
4	B	14118285	344.80	46.67	47.04	2.78
	A	305057	7.39
	B	14198116	346.75	48.50
	A	295231	7.15
	B	14093721	344.20	45.96
	A	309151	7.49

System 1: ethyl acetate/0.5% phosphoric acid; 2: ethyl acetate/1.0% phosphoric acid; 3: ethyl acetate/3.0% phosphoric acid; 4: ethyl acetate/5.0% phosphoric acid; ^AC: the organic phase; and ^BC: the aqueous phase.