A Rapid Screening Method for Sibutramine Hydrochloride in Natural Herbal Medicines and Dietary Supplements

Table 8

The determination of detection limit.

Sample	Concentration of sibutramin hydrochloride (mg/ml)	Precipitate formed
1	0	No
2	0.008	No
3	0.010	No
4	0.012	Not sure
5	0.025	Yes
6	0.050	Yes
7	0.100	Yes

When testing sibutramine within a dietary supplement, it was determined that 0.025 mg/ml sibutramine hydrochloride was the lowest visually detectable limit.