Long-Term Stability of Hydromorphone in Human Plasma Frozen at −20°C for Three Years Quantified by LC-MS/MS

<div>Chromatograms of a patient sample measured in 2016 (two upper panels) and 2019 (two lower panels). The signal of hydromorphone is shown in the top panel each and the signal of internal standard hydromorphone-D3 is shown in the bottom panel each, respectively.</div>

International Journal of Analytical Chemistry

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Figure 5

Figure 5: Long-Term Stability of Hydromorphone in Human Plasma Frozen at −20°C for Three Years Quantified by LC-MS/MS 