The Value of Peripheral Blood Leukocyte Parameters in the Early Diagnosis and Clinical Prognosis of Sepsis

Table 4

Efficacy evaluation of leukocyte parameters in differential diagnosis between sepsis and nonseptic infection.

Leukocyte parameters	AUC (95%CI)	Cut-off	Se (%)	Sp (%)	PPV (%)	NPV (%)
LYMPH#	0.686 (0.580, 0.791)	0.84	75.60	56.60	59.67	73.21
HFLC#	0.751 (0.652, 0.849)	0.03	53.30	88.70	80.02	69.11
NE-WX	0.722 (0.617, 0.827)	331.50	57.80	86.80	78.80	70.78
LY-WX	0.677 (0.571, 0.784)	506.50	77.80	54.70	59.32	74.37
LY-WY	0.713 (0.612, 0.814)	954.00	64.40	69.80	64.42	69.78
MO-WX	0.657 (0.549, 0.765)	276.50	55.60	71.70	62.52	65.54
IG#	0.724 (0.619, 0.829)	0.09	64.40	79.20	72.44	72.38
LYMPH# + HFLC# + NE-WX + LY-WX + LY-WY + MO-WX + IG#	0.829 (0.739, 0.913)	0.62	82.20	77.40	75.54	83.66

Abbreviations. AUC, area under the receiver operating characteristic curve; CI, confidence interval; Se, sensitivity, Sp, specificity; PPV, positive pretest value; NPV, negative pretest value.