Quantitative Analysis of Favipiravir by HPLC: Development and Validation

Table 5

Favipiravir sensitivity showing LOD and LOQ.

Conc (%)	Conc. (ppm)	Injection area repetition 1	Injection area repetition 2	Injection area repetition 3	Average area
5.0	0.0250	0.018	0.019	0.018	0.018
12.5	0.0625	0.046	0.045	0.047	0.046
25.0	0.1250	0.093	0.094	0.092	0.093
50.0	0.2500	0.185	0.186	0.187	0.186
100.0	0.5000	0.374	0.373	0.373	0.373
150.0	0.7500	0.562	0.558	0.56	0.560
200.0	1.0000	0.746	0.747	0.747	0.747
STEYX		0.001	0.001	0.001	0.001
Slope		0.7480	0.7464	0.7474	0.747
LOQ (ppm)		0.0156	0.0151	0.0084	0.0130
LOD (ppm)		0.0051	0.0050	0.0028	0.0043