Comparing Jaffe and Enzymatic Methods for Creatinine Measurement at Various Icterus Levels and Their Impacts on Liver Transplant Allocation

Table 1

Characteristics of methods used in the study.

Analytes	Method	Reagent	Wavelength (nm)	Analytical sensitivity (mg/dL)	Linearity limit (mg/dL)	Limit of icterus interference, bilirubin (mg/dL)
Creatinine	Jaffe	BIOREX	500	0.2	20	4
Creatinine	Enzymatic (creatinine deiminase)	BIOREX	340	0.2	20	15
Bilirubin	Jendrassik- Grof	BIOREX	546	0.1	25	—

IBM SPSS (version 25.0) was used to analyze all the data. Quantitative variables were expressed as mean ± SD and/or median (range). Significance testing was 2-sided and set to less than 0.05. The Wilcoxon signed-rank test was used for a nonparametric comparison between paired Cr values and paired MELD scores. The Mann–Whitney U test was used to determine how the mean values differed.