International Journal of Alzheimer’s Disease / 2009 / Article / Tab 3

Research Article

Risk of Dementia Associated with Elevated Plasma Homocysteine in a Latin American Population

Table 3

Comparison of risk associated with total homocysteine (tHcy) for Alzheimer’s disease (AD) and vascular dementia (VaD).


GroupRisk factorCases/TotalOR95% CICases/TotalOR95% CI

ADlog(tHcy)74/2005 2.5–7.565/17011.90.9–4.2
VaDlog(tHcy)48/1979 4.1–15.145/1681 2.0–11.1

Adjusted model includes age, sex, education, diabetes, folate, vitamin B12, and APOE genotype; , criteria from the NINCDS/ADRDA [34] were used to diagnose AD and criteria from the ADDTC [35] to diagnose VaD.

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