Research Article

Amyloid Beta Annular Protofibrils in Cell Processes and Synapses Accumulate with Aging and Alzheimer-Associated Genetic Modification

Figure 1

The labeling pattern of the anti-annular protofibril ( APF) antiserum and anti-A N-terminal pAb in serial sections of aged mouse brain (embedded in paraffin) by light microscopy. DAB method, 100x. Cap, capillary. (a) No immunoreaction (IR) for APF antiserum was observed. (b) Anti-A N-terminal pAb strongly labeled senile plaques.
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(a)
689285.fig.001b
(b)