Plasma copper levels (mean ± SEM) in human AD and control subjects. Plasma copper is significantly increased in female AD () compared to male AD () (). There is a trend to increased plasma copper in old female control subjects () compared to old male control subjects () () and in female middle-aged control subjects () compared to middle-aged male control subjects () (). When all healthy control subjects in each gender are combined, there is a significant difference in plasma copper (, see text).
