E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity
Figure 4
Neurotoxicity of Aβ40, Aβ42, E22Δ-Aβ40, E22Δ-Aβ42, and E22P-Aβ42 with the indicated concentration (1, 2, 5, 10, and 20 μM) using primary rat cortical neuronal cell cultures after 48-hr incubation at 37°C. Data are expressed as the mean ± s.e.m. versus vehicle, versus vehicle. Veh: vehicle.
