Cerebrospinal Fluid Levels of sAPPα and sAPPβ in Lewy Body and Alzheimer's Disease: Clinical and Neurochemical Correlates

Table 1

Demographic and clinical characteristics of the diagnostic groups.

Diagnosis groups	NC (𝑛=12)	AD (𝑛=50)	DLB (𝑛=24)	PDD (𝑛=21)	P
Gender (F/M)	7/5	30/20	7/17	7/14	0.034
Age, y	74.1 (8.3)	74.4 (8.1)	74.0 (7.1)	73.6 (7.0)	—
MMSE	28.6 (0.9)	21.1 (4.9)	21.8 (4.0)	20.4 (4.9)	0.000^(1)
Disease duration, y	Na	2.2 (1.3)	4.1 (3.1)	7.0 (4)	0.0002^(2)
Education, y	10.2 (3.0)	10.1 (.3.) (𝑛=27)	9.3 (2.4)	9.3 (2.8)	0.8

NC: normal controls, AD: Alzheimer’s disease, DLB: dementia with Lewy bodies, PDD: Parkinson’s disease dementia; Na: not applicable.
Numbers represent mean (standard deviation) or number of patients.
⁽¹⁾ Significant difference between NC and the disease groups. No significant difference between disease groups.
⁽²⁾ Significant difference between PDD and the two other disease groups. No significant difference between DLB and AD.