Figure 3: A schematic representation of clathrin-mediated endocytosis and intracellular transport pathways. Alzheimer’s disease susceptibility genes returned from very large genomewide association studies are in black, and those from the pre-GWAS era in grey. Binding interactions are indicated by linked diamonds and other effects by arrows. C. Pneu: chlamydia pneumoniae; H. Pyl: Helicobacter pylori; P. Ging: Porphyromonas gingivalis; black star: Herpes simplex: see text for details.