Conjugated Quantum Dots Inhibit the Amyloid β (1–42) Fibrillation Process
Figure 9
(a) ThT fluorescence after 7 days of incubation at 37°C for Aβ (1–42) (■); ThT assay after 7 days of incubation at 37°C for Aβ (1–42) mixed DHLA-capped QDs (•); ThT assay after 7 days of incubation at 37°C for Aβ (1–42) conjugated DHLA-capped QDs (▴);10 μM Thioflavin T (♦); 0.96 μM Aβ (1–42) (▾); (b) thioflavin T fluorescence monitored over a period of 7 days for incubated samples of pure Aβ (1–42) in comparison to Aβ (1–42) mixed and conjugated to QDs; (c) tyrosine emission intensity of the Aβ (1–42) at excitation wavelength 280 nm, quenched in the presence of QDs.
