Diagnostic Utility of CSF Tau and A𝜷_𝟒𝟐 in Dementia: A Meta-Analysis

Table 3

Pooled estimate of effect size with 95% CI, test of significance and magnitude of heterogeneity of CSF tau studies in Alzheimer’s disease and Dementia due to other causes.

Statistics	Alzheimer’s disease	Dementia due to other causes
Pooled estimate of CSF tau (pg/mL)	414.073	83.500
95% CI of pooled estimate (pg/mL)	237.170–590.975	36.406–130.595
Between-studies variance (𝑇^2)	85013.958	4343.165
Degree of heterogeneity (𝐼^2)	97.9%	82.4%
95% CI of 𝐼^2	97.2%–98.4%	69.7%–89.7%
Q statistics	467.756	56.738
DF	10	10
𝑃 value	0.000	0.000