International Journal of Alzheimer’s Disease / 2011 / Article / Fig 1

Review Article

Possible Role of the Transglutaminases in the Pathogenesis of Alzheimer's Disease and Other Neurodegenerative Diseases

Figure 1

Transglutaminase-catalyzed reactions. Examples of TG-catalyzed reactions: (a) acyl transfer between the γ-carboxamide group of a protein/polypeptide glutaminyl residue and the ε-amino group of a protein/polypeptide lysyl residue; (b) attachment of a polyamine to the carboxamide group of a glutaminyl residue; (c) deamidation of the γ-carboxamide group of a protein/polypeptide glutaminyl residue.
865432.fig.001a
(a)
865432.fig.001b
(b)
865432.fig.001c
(c)

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