International Journal of Alzheimer’s Disease / 2011 / Article / Fig 1

Research Article

Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis

Figure 1

Amyloid precursor protein (APP) cleavage and mutation. The present diagram represent APP, a transmembrane protein precursor of Aβ peptide, with the three principal cleavage site (β-secretase or BACE, α-secretase, and γ-secretase) and several known mutations.

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