International Journal of Alzheimer’s Disease

Research Article

Early Detection of Brain Pathology Suggestive of Early AD Using Objective Evaluation of FDG-PET Scans

Table 2

Results for subjects enrolled in the MCI early detection study.
SubjectMMSESMLDxSPM1SPM2PET1PET212345
S00130−−−−−−
S00530−−−—−—−−
S00628−−−−−−−
S00829−−−−−−n±n±nc−
S01730−−−−−−cc±na
S02030−−−−−−±n±nc±n±n
S02529−−−−−−n±nn
S00927−−±+−−±n−
S00228−−+±++c±n±nc
S00327−−++−−n±nn±n
S01230+−++−+
S03929+(±nMCI)−−−−±n−
S01529+nMCI−−−−na±n−
S02828+nMCI−−−−±n±na±n−
S01930+nMCI−−−−n±n±n±n
S02728+cMCI−−−−cacca
S03429+cMCI−−+−ccca
S01029+cMCI−±+cacac
S01430+(cMCI)+++−c±n±a
S01627+(cMCI)±+−−c±n±a
S01829+aMCI±−−−±aac±a−
S02230+cMCI++−−caaca
S01328+(±nMCI)+++−+±n±n±n
S02325+cMCI+++−−ccccc
S02129+nMCI++++−−n±ncc
S03227+cMCI+++—+—cccc−
S03122+AD+++—+—ccccc
S03325+AD+++—+—cc−−−
S03825+AD+++—+—c−−−−
S04025+AD+++—+—ccc−−
S04126+AD++++++−−ccccc
Subj: Subject ID, MMSE: Mini-mental State Exam score, SML: subjective memory loss, Dx: Diagnosis, SPM: Consistent with possible MCI/AD based on inspection of SPM statistical map, PET: Consistent with possible MCI/AD based on inspection of PET scan. There were two PET scans obtained for each patient. One at study initiation and one at the end of the three year study. These are represented by the “1’’ and “2’’ subscripts for SPM and PET, respectively. NP testing was done at five timepoints during the three year study, and results for these five examinations are shown in the columns on the right (1 through 5). NP testing: (blank): normal, a: amnestic, n: nonamnestic, (−): no data.