Association between the c. 2495 A>G ATP7B Polymorphism and Sporadic Alzheimer's Disease
Figure 1
Analytical procedures for ATP7B SNPs detection. (a) PCR-restriction fragment length polymorphism (RFLP) assay for detection of c.1216 T>G SNP. Lane 1 : PCR 100 bp low ladder. Lane 2 : GG genotype (375 bp and 209 bp RFLP). Lane 3 : TG genotype (584 bp, 375 bp and 209 bp RFLP). Lane 4 : TT genotype (584 bp RFLP). In the electropherogram the arrow indicates the TG genotype. (b) TaqMan allelic discrimination assays for detection of c.2495 A>G SNP. Blue: AA genotype. Green: TG genotype. Red: GG genotype; x: undetermined.
