Association between the c. 2495 A>G ATP7B Polymorphism and Sporadic Alzheimer's Disease

Table 3

c.1216 T>G ATP7B (exon 2) SNP allele distribution in AD patients and healthy controls and comparison of GG versus TG+TT.

c.1216 T>G ATP7B (exon 2)	AD patients (162)	Controls (123)	P value
Allele T frequency n (%)	160 (49%)	137 (55.7%)	𝜒^2=2.23;df=1; 𝑃=.13
Allele G frequency n (%)	164 (51%)	109 (44.3%)
GG n (%)	41 (25.3%)	24 (19.5%)	𝑃=.074^∗
TG+TT n (%)	121 (74.7%)	99 (80.5%)

Correlation is significant at the .05 level (2-tailed). *The analyses were corrected for the age effect.