International Journal of Alzheimer’s Disease / 2012 / Article / Tab 3 / Research Article
Japanese Alzheimer’s Disease and Other Complex Disorders Diagnosis Based on Mitochondrial SNP Haplogroups Table 3 (a) mtDNA mutations for the haplogroups of the AD patients, (b) mtDNA mutations for the haplogroups of the PD patients, (c) mtDNA mutations for the haplogroups of the T2D patients, (d) mtDNA mutations for the haplogroups of the T2D patients with angiopathy, (e) mtDNA mutations for the haplogroups of the centenarians, (f) mtDNA mutations for the haplogroups of the semi-supercentenarians, (g) mtDNA mutations for the haplogroups of the non-obese young males, (h) mtDNA mutations for the haplogroups of the obese young males.
(a) mtDNA locus Normal nucleotide mtDNA mutation AD patients G2a N9b1 709 G A A 4833 A G G 5108 T C C 5147 G A A 5417 G A A 5601 C T T 7600 G A A 9377 A G G 9575 G A A 10607 C T T 11016 G A A 13183 A G G 13563 A G G 14200 T C C 14569 G A A 14893 A G G 16278 C T T 16362 T C C 16519 T C C
(b) mtDNA locus Normal nucleotide mtDNA mutation PD patients M7a1a G1a B5b N9a 150 C T T T 204 T C C 709 G A A 1598 G A A 2626 T C C 2772 C T T 4386 T C C 4958 A G G 5231 G A A 5417 G A A 7867 C T T 8020 G A A 8584 G A A 9950 T C C 11017 T C C 11084 A G G 12358 A G G 12361 A G G 12372 G A A 12771 G A A 14364 G A A 15223 C T T 15323 G A A 15851 A G G 15927 G A A 16140 T C C 16209 T C C 16243 T C C 16257 C A A 16261 C T T 16324 T C C 16519 T C C
(c) mtDNA locus Normal nucleotide mtDNA mutation T2D patients M8a D4b2b B5b 194 C T T 204 T C C 709 G A A 1382 A C C 1598 G A A 3010 G A A 4715 A G G 4883 C T T 5178 C A A 6179 G A A 7196 C A A 8020 G A A 8414 C T T 8584 G A A A 8684 C T T 8829 C T T 8964 C T T 9296 C T T 9824 T A A 9950 T C C 12361 A G G 14470 T C C 14605 A G G 14668 C T T 15223 C T T 15487 A T T 15508 C T T 15662 A G G 15851 A G G 15927 G A A 16140 T C C 16243 T C C 16298 T C C 16319 G A A 16519 T C C C
(d) mtDNA locus Normal nucleotide mtDNA mutation T2D patients with angiopathy G2a D4b1 N9a2 150 C T T 709 G A A 3010 G A A 4833 A G G 4883 C T T 5108 T C C 5178 C A A 5231 G A A 5417 G A A 5601 C T T 7600 G A A 8020 G A A 8414 C T T 9377 A G G 9575 G A A 10181 C T T 12358 A G G 12372 G A A 13563 A G G 14569 G A A 14668 C T T 15440 T C C 15951 A G G 16172 T C C 16257 C A A 16261 C T T 16278 C T T 16319 G A A 16362 T C C C 16519 T C C C C
(e) mtDNA locus Normal nucleotide mtDNA mutation Centenarians M7b2 D4b2a B5b 150 C T T 199 T C C 204 T C C 709 G A A 1382 A C C 1598 G A A 3010 G A A 4048 G A A 4071 C T T 4164 A G G 4883 C T T 5178 C A A 5351 A G G 5460 G A A 6455 C T T 6680 T C C 7684 T C C 7853 G A A 8020 G A A 8251 G A A 8414 C T T 8584 G A A 8829 C T T 8964 C T T 9824 T A A 9824 T C C 9950 T C C 10104 C T T 10345 T C C 12361 A G G 12405 C T T 12705 C T T 12811 T C C 14668 C T T 15223 C T T 15508 C T T 15662 A G G 15851 A G G 15927 G A A 16129 G A A 16140 T C C 16223 C T T 16243 T C C 16297 T C C 16298 T C C 16362 T C C 16519 T C C C
(f) mtDNA locus Normal nucleotide mtDNA mutation Semi-supercentenarians M1 B4c1a B4c1b1 B4c1c1 F1 150 C T T T 195 T C C C 709 G A A 1119 T C C C C 1621 T C C C C 3497 C T T T 3970 C T T 6392 T C C 6962 G A A 10310 G A A A 10398 A G G 10609 G A A 12406 G A A 12705 C T T T T T 12802 C T T 13928 G C C 15346 G A A 16140 T C C 16217 T C C C C 16223 C T T T T T 16249 T C C 16274 G A A 16311 T C C C 16519 T C C C C C
(g) mtDNA locus Normal nucleotide mtDNA mutation Non-obese young males D4b2b D4g B4b/d/e N9a 150 C T T 194 C T T 827 A G G 1382 A C C 3010 G A A 4343 A G G 4883 C T T T 5178 C A A A 5231 G A A 5417 G A A 8020 G A A 8414 C T T 8701 A G G 8964 C T T 9296 C T T 9824 T A A 12358 A G G 12372 G A A 12705 C T T 13104 A G G 14668 C T T T 15518 C T T 15535 C T T 16217 T C C 16223 C T T 16257 C A A 16261 C T T 16278 C T T 16362 T C C C 16519 T C C C C C
(h) Obese young males mtDNA locus Normal nucleotide mtDNA mutation M7a1a M7b2 D4b2b B4c1 150 C T T 194 C T T 199 T C C 709 G A A 1119 T C C 1382 A C C 2626 T C C 2772 C T T 3010 G A A 3497 C T T 4048 G A A 4071 C T T 4164 A G G 4386 T C C 4883 C T T 4958 A G G 5178 C A A 5351 A G G 5460 G A A 6455 C T T T 6680 T C C 7684 T C C 7853 G A A 8020 G A A 8964 C T T 9296 C T T 9824 T A A 10345 T C C 12405 C T T 12705 C T T 12771 G A A 12811 T C C 14668 C T T 15346 G A A 16129 G A A 16209 T C C 16217 T C C 16223 C T T 16297 T C C 16298 T C C 16324 T C C 16362 T C C 16519 T C C C