Research Article
Japanese Alzheimer’s Disease and Other Complex Disorders Diagnosis Based on Mitochondrial SNP Haplogroups
Table 4
Differences between the statistical technique and the proposed (modified RBF) method.
| | Statistical technique | Proposed method |
| Technique | Relative relations between target and normal data | Supervised learning (RBF) by using correct and incorrect data | Analysis position | Each locus of mtDNA polymorphisms (independent position) | Entire loci of mtDNA polymorphisms (succesive positions) | Input (required data) | Target (individual cases) and control (normal data) | Correct (individual cases) and incorrect (others except correct) | Output (results) | Odds ratio or relative risk | Clusters with predictions | Analysis | Check odds ratio or relative risk at each position | Check individuals in clusters based on prediction probabilities |
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