Japanese Alzheimer’s Disease and Other Complex Disorders Diagnosis Based on Mitochondrial SNP Haplogroups

Table 4

Differences between the statistical technique and the proposed (modified RBF) method.

	Statistical technique	Proposed method
Technique	Relative relations between target and normal data	Supervised learning (RBF) by using correct and incorrect data
Analysis position	Each locus of mtDNA polymorphisms (independent position)	Entire loci of mtDNA polymorphisms (succesive positions)
Input (required data)	Target (individual cases) and control (normal data)	Correct (individual cases) and incorrect (others except correct)
Output (results)	Odds ratio or relative risk	Clusters with predictions
Analysis	Check odds ratio or relative risk at each position	Check individuals in clusters based on prediction probabilities