Review Article

Microglial Scavenger Receptors and Their Roles in the Pathogenesis of Alzheimer's Disease

Figure 1

Structural diversity of the scavenger receptors. SCARA have a collagen-like domain believed to be their ligand-binding domain. CD68 has a mucin-like domain; LOX-1(oxidized-low density lipoprotein (lectin-like) receptor-1) (SCARE) has a C-type lectin domain and binds oxidized LDL. SCARF (scavenger receptor class F) has multiple extracellular EGF-like repeats.
489456.fig.001