Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics

Figure 3

APOE-related systolic blood pressure response to a multifactorial therapy in patients with dementia. Tb: basal systolic blood pressure (SBP) prior to treatment; Tt: SBP after 3 months of treatment in the total sample. E2/3b: basal SBP in APOE-2/3 carriers; E2/3t: SBP after treatment in APOE-2/3 carriers; E2/4b: basal SBP in APOE-2/4 carriers; E2/4t: SBP after treatment in APOE-2/4 carriers; E3/3b: basal SBP in APOE-3/3 carriers; E3/3t: SBP after treatment in APOE-3/3 carriers; E3/4b: basal SBP in APOE-3/4 carriers; E3/4t: SBP after treatment in APOE-3/4 carriers; E4/4b: basal SBP in APOE-4/4 carriers; E4/4: SBP after treatment in APOE-4/4 carriers.