Stimulation-Dependent Intraspinal Microtubules and Synaptic Failure in Alzheimer's Disease: A Review
Figure 2
Redistribution of microtubules in dendritic spines after stimulation. There were little microtubules and thin postsynaptic densities (black arrows in (a)) in a nonstimulated slice (a). Many microtubules (white arrows in (b)) concentrated to three thickened PSDs (black arrows 1, 2, and 3 in (b)) in spines have emerged after stimulation (b). The planes of PSD1, 2, and 3 are perpendicular, oblique, and parallel to this electron microscopic section, respectively. Reprinted from Mitsuyama et al. (2008) [21] with permission. Bar, 150 nm.
