Bupropion and Citalopram in the APP23 Mouse Model of Alzheimer's Disease: A Study in a Dry-Land Maze

Table 1

Two-way ANOVA for total, resting and moving time for APP23 animals with treatment groups sham treatment (sham), bupropion treatment (bup), and citalopram treatment (cit). Post hoc multiple comparison testing (Fisher LSD) with 𝑃 values for comparison of differences between groups. *Indicates statistical significance.

	Mean	SEM		Between group 𝑃 value
				To sham	To bup
Total time
sham	174.8	11.3
bup	116.5	8.8		<0.001*	—
cit	174.2	11.6		0.964	<0.001*
Resting time
sham	104.9	8.1
bup	55.1	5.6		<0.001*	—
cit	103.8	8.7		0.912	<0.001*
Moving time
sham	69.9	3.7
bup	61.4	3.7		0.081	—
cit	70.4	4.0		0.926	0.066