Research Article

Effects of Copper and/or Cholesterol Overload on Mitochondrial Function in a Rat Model of Incipient Neurodegeneration

Figure 5

Levels of lipoperoxides (LPOO) (a) and conjugated dienes (b) in mitochondrial fractions from brain cortex and hippocampus. Results are expressed as μmoles of LPOO/μMoles of Pi in CL, or UDO/mg protein, respectively. Treatments are indicated with different colors, control (white bars), Cu (black bars), Cho (gray bars), and CuCho (dark gray bars). Samples were analyzed as indicated in Sections 2.13.1 and 2.13.2. Results are the mean of 10 rats assayed in triplicate ± standard deviation (SD). Significant differences among data are indicated with superscript letters (values with distinct letters are significantly different between them, ).
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(a)
645379.fig.005b
(b)