Research Article

Effects of Copper and/or Cholesterol Overload on Mitochondrial Function in a Rat Model of Incipient Neurodegeneration

Figure 6

Cardiolipin (CL) (a) and lyso-CL (LCL) (b) levels in mitochondrial fractions from brain cortex and hippocampus (μmoles of Pi/mg total protein). Treatments are indicated with different colors, control (white bars), Cu (black bars), Cho (gray bars), and CuCho (dark gray bars). Samples were analyzed as indicated in Section 2.7. Results are the mean of 10 rats assayed in triplicate ± standard deviation (SD). Significant differences among the experimental groups are indicated with superscript letters (values with distinct letters are significantly different between them, ).
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(a)
645379.fig.006b
(b)