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International Journal of Alzheimer’s Disease
Volume 2013 (2013), Article ID 823528, 14 pages
http://dx.doi.org/10.1155/2013/823528
Research Article

In Vivo Characterization of a Novel -Secretase Inhibitor SCH 697466 in Rodents and Investigation of Strategies for Managing Notch-Related Side Effects

1Department of Neuroscience, Merck Research Laboratories, Kenilworth, NJ 07033, USA
2Department of Molecular Biomarkers, Merck Research Laboratories, Kenilworth, NJ 07033, USA
3Department of Medicinal Chemistry, Merck Research Laboratories, Kenilworth, NJ 07033, USA
4Department of Drug Metabolism and Pharmoackinetics, Merck Research Laboratories, Kenilworth, NJ 07033, USA

Received 29 August 2012; Accepted 27 November 2012

Academic Editor: Jeremy Toyn

Copyright © 2013 Lynn A. Hyde et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Lynn A. Hyde, Qi Zhang, Robert A. Del Vecchio, et al., “In Vivo Characterization of a Novel -Secretase Inhibitor SCH 697466 in Rodents and Investigation of Strategies for Managing Notch-Related Side Effects,” International Journal of Alzheimer’s Disease, vol. 2013, Article ID 823528, 14 pages, 2013. doi:10.1155/2013/823528