The Association between Apolipoprotein E Gene Polymorphism and Mild Cognitive Impairment among Different Ethnic Minority Groups in China
Table 1
Characteristics of the studied population.
Total ( = 924)
Hui ( = 306)
Han ( = 618)
value*
Age, mean (SD), and years
66.4 (6.6)
65.4 (6.8)
66.9 (6.5)
0.001
Gender, female, (%)
571 (61.8)
183 (59.8)
388 (62.7)
0.380
Education, (%)
No formal education
239 (25.9)
106 (34.6)
133 (21.5)
<0.001
Primary school
253 (27.4)
89 (29.1)
164 (26.5)
Junior high school
254 (27.5)
69 (22.5)
185 (29.9)
Senior high school or above
178 (19.3)
42 (13.7)
136 (22.0)
Living arrangement, alone, (%)
187 (20.2)
48 (15.7)
139 (22.5)
0.015
Smoking, yes, (%)
218 (23.6)
48 (15.6)
170 (27.5)
<0.001
Alcohol use, yes, (%)
115 (12.4)
14 (4.5)
101 (16.3)
<0.001
TC mean (SD) (mmol/L)
4.7 (0.9)
4.6 (1.0)
4.8 (0.9)
0.051
TG mean (SD) (mmol/L)
1.8 (0.8)
1.7 (0.9)
1.8 (0.8)
0.273
HDL mean (SD) (mmol/L)
4.0 (1.0)
4.0 (1.0)
4.0 (1.0)
0.738
LDL mean (SD) (mmol/L)
3.2 (0.6)
3.2 (0.7)
3.2 (0.6)
0.307
SBP mean (SD) (mmHg)
149.7 (20.4)
151.2 (20.9)
148.9 (20.2)
0.104
DBP mean (SD) (mmHg)
87.0 (11.5)
88.5 (11.4)
86.3 (11.4)
0.005
MCI, yes, (%)
181 (19.6)
66 (21.5)
115 (18.6)
0.286
apoE genotype (%)
2/2
19 (2.1)
8 (2.6)
11 (1.8)
0.517
2/3
122 (13.2)
39 (12.4)
83 (13.4)
2/4
3 (0.3)
2 (0.7)
1 (0.2)
3/3
715 (77.4)
237 (77.2)
479 (77.5)
3/4
58 (6.3)
17 (5.5)
41 (6.6)
4/4
7 (0.8)
4 (1.3)
3 (0.5)
apoE allele frequency, (%)
2
163 (8.8)
57 (9.3)
106 (8.6)
0.752
3
1,612 (87.1)
530 (86.3)
1082 (87.5)
4
75 (4.0)
27 (4.4)
48 (3.9)
4 carrier, yes, (%)
68 (7.4)
23 (7.5)
45 (7.2)
0.898
2 carrier, yes, (%)
144 (15.6)
49 (16.0)
95 (15.4)
0.800
Risk index, mean (SD)
0.1 (0.5)
0.1 (0.5)
0.1 (0.5)
0.913
value of Hui with Han; TC: total cholesterol; TG: triglyceride; HDL: high density lipoprotein; LDL: low density lipoprotein; SBP: systolic blood pressure; DBP: diastolic blood pressure.
