Research Article
The Association between Apolipoprotein E Gene Polymorphism and Mild Cognitive Impairment among Different Ethnic Minority Groups in China
Table 2
Bivariate association between apoE
4 allele and MCI.
| | Total () | MCI | value | | NO ( = 743) | Yes ( = 181) |
| | Allele frequency, (%) | | | | | 2 | 139 (9.4) | 24 (6.6) | <0.001 | | 3 | 1299 (87.4) | 311 (85.9) | | 4 | 48 (3.2) | 27 (7.5) | | 2 carrier, yes, (%) | 123 (16.6) | 21 (11.6) | 0.100 | | 4 carrier, yes, (%) | 42 (5.7) | 26 (14.4) | <0.001 | | Risk index, mean (SD) | 0.1 (0.5) | −0.0 (0.5) | 0.002 |
| | Hui ( = 306) | NO ( = 240) | Yes ( = 66) | |
| | Allele frequency, (%) | | | | | 2 | 46 (9.6) | 11 (8.3) | <0.001 | | 3 | 418 (87.1) | 110 (83.3) | | 4 | 16 (3.3) | 11 (8.3) | | 2 carrier, yes, (%) | 39 (16.25) | 10 (15.1) | 0.829 | | 4 carrier, yes, (%) | 13 (5.4) | 10 (15.1) | 0.008 | | Risk index, mean (SD) | 0.1 (0.5) | 0.0 (0.6) | 0.118 |
| | Han ( = 618) | NO ( = 503) | Yes ( = 115) | |
| | Allele frequency (%) | | | | | 2 | 93 (9.2) | 13 (5.7) | <0.001 | | 3 | 881 (87.6) | 201 (87.4) | | 4 | 32 (3.2) | 16 (7.0) | | 2 carrier, yes, (%) | 84 (16.6) | 11 (9.5) | 0.056 | | 4 carrier, yes, (%) | 29 (5.7) | 16 (13.9) | 0.002 | | Risk index, mean (SD) | 0.1 (0.5) | 0.0 (0.5) | 0.007 |
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