Spectral Analysis of EEG in Familial Alzheimer’s Disease with E280A Presenilin-1 Mutation Gene

Table 1

Demographic and neuropsychological data of interest of normal, ACr, and probable AD subjects.

	Normal	ACr	Probable AD	Anova
𝑁	18	21	18
Age (years)	41.8 (±7.5 SE)	39.9 (±7.30 SE)	49 (±5.03 SE)	F = 9.46, df = 2.54; P  <  0.0002
Gender (F/M)	14/4	14/7	9/9
MMSE	28.8 (±1.23 SE)	28.2 (±1.84 SE)	21.1 (±2.44 SE)	F = 67.52, df = 2.54; P  <  0.0000
Education (years)	6.33 (±2.95 SE)	7.28 (±4.14 SE)	6.22 (±4.02 SE)	F = 0.47, df = 2.54; P < 0.62
IAF	9.36 (±0.63 SE)	9.41 (±0.9 SE)	8.72 (±0.9 SE)	F = 8.51, df = 2.54; P  <  0.0006

MMSE: mini-mental scale examination; IAF: individual alpha frequency; SE: standard error; F: female; M: male; df: degree of freedom.