Research Article

High-Dimensional Medial Lobe Morphometry: An Automated MRI Biomarker for the New AD Diagnostic Criteria

Figure 2

Intensity standardization example for an ADNI subject. From left to right: (a) reference image; (b) original image; (c) standardized image using the Nyul et al. histogram-matching technique [41]; and (d) standardized image using our tissue derived, spatially constrained intensity matching technique [42]. The color map was chosen to increase contrast.
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278096.fig.002b
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