Neprilysin Is Poorly Expressed in the Prefrontal Cortex of Aged Dogs with Cognitive Dysfunction Syndrome
Figure 1
Agarose gel electrophoresis of RT-PCR of NEP, IDE, and Ubi arranged by groups ((a) young, (b) aged-CU and (c) aged-CI). Amplicons of NEP cDNA (625 bp band) in young (a) and aged-CU (b) animals showed considerable intragroup variability; in contrast in aged-CI dogs (c), there are lower levels of NEP with less variability. IDE amplicons (493 bp band) present high intensity of band with similar levels in all animals. Ubi was included as an internal standard.
