Structural Brain Imaging Phenotypes of Mild Cognitive Impairment (MCI) and Alzheimer’s Disease (AD) Found by Hierarchical Clustering

Table 3

The clusters with the lowest average diagnosis (, , ).

Cluster number	Females	Males	NC	MCI	AD	Average diagnosis	APOE prev. %	Declining status %	Mean education years	Mean ADAS score	Mean age	Mean ADAS slope	STD of ADAS slopes
1	22	18	18	22	0	1.55	35.0	27.5	16.1	11.6	74.3	-0.049	0.189
2	17	19	17	15	4	1.64	41.7	34.4	16.1	14.4	73.8	0.057	0.183
3	93	66	71	80	8	1.60	37.7	23.2	16.4	12.6	73.6	0.062	0.434
4	38	39	36	34	7	1.62	31.2	11.4	16.0	12.0	74.7	0.016	0.156
5	16	31	30	17	0	1.36	36.2	17.0	16.1	11.5	76.6	0.017	0.172
6	5	20	10	15	0	1.60	32.0	20.0	15.8	13.3	70.9	-0.040	0.246
7	8	8	8	7	1	1.56	37.5	13.3	17.8	10.8	73.7	0.011	0.179
8	1	7	4	4	0	1.50	25.0	25.0	16.8	9.1	71.8	-0.037	0.142
9	7	6	8	5	0	1.38	15.4	15.4	16.8	10.8	72.3	-0.020	0.156
10	5	17	9	12	1	1.64	31.8	19.0	16.6	13.9	75.1	0.012	0.143
11	3	4	4	3	0	1.43	14.3	14.3	16.0	13.7	80.1	-0.014	0.167
12	3	8	9	2	0	1.18	9.1	9.1	17.0	10.8	71.8	-0.042	0.133